Why Are C-Section Deliveries Linked to Childhood Type 1 Diabetes?

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Why Are C-Section Deliveries Linked to Childhood Type 1 Diabetes?

The incidence of type 1 diabetes (T1D) is increasing worldwide at an annual rate of 3.9% (1). Early life factors have been shown to be associated with increased T1D risk and perhaps involved in the development of the immune system (2). Cesarean section (C-section) deliveries have increased by 50% since the 1990s (3) and have paralleled the increasing trend in the incidence of T1D (4). A recent ...

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Cesarean Section and Interferon-Induced Helicase Gene Polymorphisms Combine to Increase Childhood Type 1 Diabetes Risk

OBJECTIVE The incidence of type 1 diabetes is increasing. Delivery by cesarean section is also more prevalent, and it is suggested that cesarean section is associated with type 1 diabetes risk. We examine associations between cesarean delivery, islet autoimmunity and type 1 diabetes, and genes involved in type 1 diabetes susceptibility. RESEARCH DESIGN AND METHODS Cesarean section was examine...

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Childhood chronic urticaria and type 1 diabetes

Results We present the case of a 10 year old, otherwise healthy boy, who has a 6-7 year history of persistent chronic urticaria requiring ongoing treatment. His symptoms consist of daily urticarial lesions and angioedema with frequent flares. Upper respiratory viral infections, spring/ fall season and stressful events make his condition worse; however, no food or medication triggers has been fo...

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Childhood vaccination and type 1 diabetes.

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Type 1 diabetes is one of the most common endocrine and metabolic conditions in childhood. Treatment is life-saving and lifelong, it is painful and time-consuming, it interferes with daily life, requires self-discipline and a balanced diet. Many children and adolescents are unable to cope emotionally with their diabetes, diabetes causes them embarrasment, results in discrimination and limits so...

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ژورنال

عنوان ژورنال: Diabetes

سال: 2011

ISSN: 0012-1797,1939-327X

DOI: 10.2337/db11-1482